Brian Prendergast

Biosciences Graduate Program Association
  1. Nelson RJ, Bumgarner JR, Liu JA, Love JA, Meléndez-Fernández OH, Becker-Krail DD, Walker WH, Walton JC, DeVries AC, Prendergast BJ. Time of day as a critical variable in biology. BMC Biol. 2022 Jun 15; 20(1):142. View in: PubMed

  2. Riggle JP, Onishi KG, Love JA, Beach DE, Zucker I, Prendergast BJ. Spontaneous Recovery of Circadian Organization in Mice Lacking a Core Component of the Molecular Clockwork. J Biol Rhythms. 2022 02; 37(1):94-109. View in: PubMed

  3. Zucker I, Prendergast BJ, Beery AK. Pervasive Neglect of Sex Differences in Biomedical Research. Cold Spring Harb Perspect Biol. 2022 05 17; 14(4). View in: PubMed

  4. Zucker I, Prendergast BJ. Sex differences in pharmacokinetics predict adverse drug reactions in women. Biol Sex Differ. 2020 06 05; 11(1):32. View in: PubMed

  5. Haspel JA, Anafi R, Brown MK, Cermakian N, Depner C, Desplats P, Gelman AE, Haack M, Jelic S, Kim BS, Laposky AD, Lee YC, Mongodin E, Prather AA, Prendergast BJ, Reardon C, Shaw AC, Sengupta S, Szentirmai É, Thakkar M, Walker WE, Solt LA. Perfect timing: circadian rhythms, sleep, and immunity - an NIH workshop summary. JCI Insight. 2020 01 16; 5(1). View in: PubMed

  6. Onishi KG, Maneval AC, Cable EC, Tuohy MC, Scasny AJ, Sterina E, Love JA, Riggle JP, Malamut LK, Mukerji A, Novo JS, Appah-Sampong A, Gary JB, Prendergast BJ. Circadian and circannual timescales interact to generate seasonal changes in immune function. Brain Behav Immun. 2020 01; 83:33-43. View in: PubMed

  7. Bao R, Onishi KG, Tolla E, Ebling FJP, Lewis JE, Anderson RL, Barrett P, Prendergast BJ, Stevenson TJ. Genome sequencing and transcriptome analyses of the Siberian hamster hypothalamus identify mechanisms for seasonal energy balance. Proc Natl Acad Sci U S A. 2019 06 25; 116(26):13116-13121. View in: PubMed

  8. Onishi KG, Prendergast BJ, Stevenson TJ. Trait-specific effects of exogenous triiodothyronine on cytokine and behavioral responses to simulated systemic infection in male Siberian hamsters. Horm Behav. 2019 04; 110:90-97. View in: PubMed

  9. Prendergast BJ, Zucker I. Social Behavior: Developmental Timing Defies Puberty. Curr Biol. 2018 05 07; 28(9):R553-R555. View in: PubMed

  10. Smarr BL, Grant AD, Zucker I, Prendergast BJ, Kriegsfeld LJ. Sex differences in variability across timescales in BALB/c mice. Biol Sex Differ. 2017; 8:7. View in: PubMed

  11. Cable EJ, Onishi KG, Prendergast BJ. Circadian rhythms accelerate wound healing in female Siberian hamsters. Physiol Behav. 2017 03 15; 171:165-174. View in: PubMed

  12. Prendergast BJ, Zucker I. Ultradian rhythms in mammalian physiology and behavior. Curr Opin Neurobiol. 2016 10; 40:150-154. View in: PubMed

  13. Prendergast BJ, Cable EJ, Stevenson TJ, Onishi KG, Zucker I, Kay LM. Circadian Disruption Alters the Effects of Lipopolysaccharide Treatment on Circadian and Ultradian Locomotor Activity and Body Temperature Rhythms of Female Siberian Hamsters. J Biol Rhythms. 2015 Dec; 30(6):543-56. View in: PubMed

  14. Leone V, Gibbons SM, Martinez K, Hutchison AL, Huang EY, Cham CM, Pierre JF, Heneghan AF, Nadimpalli A, Hubert N, Zale E, Wang Y, Huang Y, Theriault B, Dinner AR, Musch MW, Kudsk KA, Prendergast BJ, Gilbert JA, Chang EB. Effects of diurnal variation of gut microbes and high-fat feeding on host circadian clock function and metabolism. Cell Host Microbe. 2015 May 13; 17(5):681-9. View in: PubMed

  15. Jarjisian SG, Butler MP, Paul MJ, Place NJ, Prendergast BJ, Kriegsfeld LJ, Zucker I. Dorsomedial hypothalamic lesions counteract decreases in locomotor activity in male Syrian hamsters transferred from long to short day lengths. J Biol Rhythms. 2015 Feb; 30(1):42-52. View in: PubMed

  16. Stevenson TJ, Prendergast BJ. Photoperiodic time measurement and seasonal immunological plasticity. Front Neuroendocrinol. 2015 Apr; 37:76-88. View in: PubMed

  17. Wang ZY, Cable EJ, Zucker I, Prendergast BJ. Pregnancy-induced changes in ultradian rhythms persist in circadian arrhythmic Siberian hamsters. Horm Behav. 2014 Jul; 66(2):228-37. View in: PubMed

  18. Bradley SP, Prendergast BJ. Adaptation to short photoperiods augments circadian food anticipatory activity in Siberian hamsters. Horm Behav. 2014 Jun; 66(1):159-68. View in: PubMed

  19. Pyter LM, El Mouatassim Bih S, Sattar H, Prendergast BJ. Peripheral tumors alter neuroinflammatory responses to lipopolysaccharide in female rats. Brain Res. 2014 Mar 13; 1552:55-63. View in: PubMed

  20. Prendergast BJ, Onishi KG, Zucker I. Female mice liberated for inclusion in neuroscience and biomedical research. Neurosci Biobehav Rev. 2014 Mar; 40:1-5. View in: PubMed

  21. Prendergast BJ, Onishi KG, Patel PN, Stevenson TJ. Circadian arrhythmia dysregulates emotional behaviors in aged Siberian hamsters. Behav Brain Res. 2014 Mar 15; 261:146-57. View in: PubMed

  22. Stevenson TJ, Onishi KG, Bradley SP, Prendergast BJ. Cell-autonomous iodothyronine deiodinase expression mediates seasonal plasticity in immune function. Brain Behav Immun. 2014 Feb; 36:61-70. View in: PubMed

  23. Stevenson TJ, Prendergast BJ. Reversible DNA methylation regulates seasonal photoperiodic time measurement. Proc Natl Acad Sci U S A. 2013 Oct 08; 110(41):16651-6. View in: PubMed

  24. Kampf-Lassin A, Prendergast BJ. Acute downregulation of Type II and Type III iodothyronine deiodinases by photoperiod in peripubertal male and female Siberian hamsters. Gen Comp Endocrinol. 2013 Nov 01; 193:72-8. View in: PubMed

  25. Prendergast BJ, Onishi KG, Zucker I. Neonatal monosodium glutamate treatment counteracts circadian arrhythmicity induced by phase shifts of the light-dark cycle in female and male Siberian hamsters. Brain Res. 2013 Jul 12; 1521:51-8. View in: PubMed

  26. Prendergast BJ, Cable EJ, Patel PN, Pyter LM, Onishi KG, Stevenson TJ, Ruby NF, Bradley SP. Impaired leukocyte trafficking and skin inflammatory responses in hamsters lacking a functional circadian system. Brain Behav Immun. 2013 Aug; 32:94-104. View in: PubMed

  27. Kampf-Lassin A, Prendergast BJ. Photoperiod history-dependent responses to intermediate day lengths engage hypothalamic iodothyronine deiodinase type III mRNA expression. Am J Physiol Regul Integr Comp Physiol. 2013 Apr 15; 304(8):R628-35. View in: PubMed

  28. Prendergast BJ, Stevenson TJ, Zucker I. Sex differences in Siberian hamster ultradian locomotor rhythms. Physiol Behav. 2013 Feb 17; 110-111:206-12. View in: PubMed

  29. Prendergast BJ, Pyter LM, Kampf-Lassin A, Patel PN, Stevenson TJ. Rapid induction of hypothalamic iodothyronine deiodinase expression by photoperiod and melatonin in juvenile Siberian hamsters (Phodopus sungorus). Endocrinology. 2013 Feb; 154(2):831-41. View in: PubMed

  30. Prendergast BJ, Cable EJ, Cisse YM, Stevenson TJ, Zucker I. Pineal and gonadal influences on ultradian locomotor rhythms of male Siberian hamsters. Horm Behav. 2013 Jan; 63(1):54-64. View in: PubMed

  31. Pyter LM, Prendergast BJ. Individual differences in pre-carcinogen cytokine and corticosterone concentrations and depressive-like behavior predict tumor onset in rats exposed to a carcinogen. Psychoneuroendocrinology. 2013 Jun; 38(6):800-7. View in: PubMed

  32. Dooley JC, Prendergast BJ. Photorefractoriness and energy availability interact to permit facultative timing of spring breeding. Behav Ecol. 2012 Sep; 23(5):1049-1058. View in: PubMed

  33. Prendergast BJ, Cisse YM, Cable EJ, Zucker I. Dissociation of ultradian and circadian phenotypes in female and male Siberian hamsters. J Biol Rhythms. 2012 Aug; 27(4):287-98. View in: PubMed

  34. Prendergast BJ, Zucker I. Photoperiodic influences on ultradian rhythms of male Siberian hamsters. PLoS One. 2012; 7(7):e41723. View in: PubMed

  35. Prendergast BJ, Beery AK, Paul MJ, Zucker I. Enhancement and suppression of ultradian and circadian rhythms across the female hamster reproductive cycle. J Biol Rhythms. 2012 Jun; 27(3):246-56. View in: PubMed

  36. Yee JR, Prendergast BJ. Endotoxin elicits ambivalent social behaviors. Psychoneuroendocrinology. 2012 Jul; 37(7):1101-5. View in: PubMed

  37. Prendergast BJ. Can photoperiod predict mortality in the 1918-1920 influenza pandemic? J Biol Rhythms. 2011 Aug; 26(4):345-52. View in: PubMed

  38. Hoffman CL, Higham JP, Heistermann M, Coe CL, Prendergast BJ, Maestripieri D. Immune function and HPA axis activity in free-ranging rhesus macaques. Physiol Behav. 2011 Sep 01; 104(3):507-14. View in: PubMed

  39. Kampf-Lassin A, Wei J, Galang J, Prendergast BJ. Experience-independent development of the hamster circadian visual system. PLoS One. 2011 Apr 27; 6(4):e16048. View in: PubMed

  40. Bradley SP, Pattullo LM, Patel PN, Prendergast BJ. Photoperiodic regulation of the orexigenic effects of ghrelin in Siberian hamsters. Horm Behav. 2010 Sep; 58(4):647-52. View in: PubMed

  41. Yee JR, Prendergast BJ. Sex-specific social regulation of inflammatory responses and sickness behaviors. Brain Behav Immun. 2010 Aug; 24(6):942-51. View in: PubMed

  42. Pyter LM, Cochrane SF, Ouwenga RL, Patel PN, Pineros V, Prendergast BJ. Mammary tumors induce select cognitive impairments. Brain Behav Immun. 2010 Aug; 24(6):903-7. View in: PubMed

  43. Prendergast BJ. MT1 melatonin receptors mediate somatic, behavioral, and reproductive neuroendocrine responses to photoperiod and melatonin in Siberian hamsters (Phodopus sungorus). Endocrinology. 2010 Feb; 151(2):714-21. View in: PubMed

  44. Prendergast BJ, Pyter LM. Photoperiod history differentially impacts reproduction and immune function in adult Siberian hamsters. J Biol Rhythms. 2009 Dec; 24(6):509-22. View in: PubMed

  45. Paul MJ, Pyter LM, Freeman DA, Galang J, Prendergast BJ. Photic and nonphotic seasonal cues differentially engage hypothalamic kisspeptin and RFamide-related peptide mRNA expression in Siberian hamsters. J Neuroendocrinol. 2009 Dec; 21(12):1007-14. View in: PubMed

  46. Pyter LM, Pineros V, Galang JA, McClintock MK, Prendergast BJ. Peripheral tumors induce depressive-like behaviors and cytokine production and alter hypothalamic-pituitary-adrenal axis regulation. Proc Natl Acad Sci U S A. 2009 Jun 02; 106(22):9069-74. View in: PubMed

  47. Prendergast BJ, Galang J, Kay LM, Pyter LM. Influence of the olfactory bulbs on blood leukocytes and behavioral responses to infection in Siberian hamsters. Brain Res. 2009 May 01; 1268:48-57. View in: PubMed

  48. Paul MJ, Galang J, Schwartz WJ, Prendergast BJ. Intermediate-duration day lengths unmask reproductive responses to nonphotic environmental cues. Am J Physiol Regul Integr Comp Physiol. 2009 May; 296(5):R1613-9. View in: PubMed

  49. Prendergast BJ, Pyter LM, Galang J, Kay LM. Reproductive responses to photoperiod persist in olfactory bulbectomized Siberian hamsters (Phodopus sungorus). Behav Brain Res. 2009 Mar 02; 198(1):159-64. View in: PubMed

  50. Prendergast BJ. Behavioral tolerance to endotoxin is enhanced by adaptation to winter photoperiods. Psychoneuroendocrinology. 2008 May; 33(4):540-5. View in: PubMed

  51. Baillie SR, Prendergast BJ. Photoperiodic regulation of behavioral responses to bacterial and viral mimetics: a test of the winter immunoenhancement hypothesis. J Biol Rhythms. 2008 Feb; 23(1):81-90. View in: PubMed

  52. Prendergast BJ, Kay LM. Affective and adrenocorticotrophic responses to photoperiod in Wistar rats. J Neuroendocrinol. 2008 Feb; 20(2):261-7. View in: PubMed

  53. Prendergast BJ, Baillie SR, Dhabhar FS. Gonadal hormone-dependent and -independent regulation of immune function by photoperiod in Siberian hamsters. Am J Physiol Regul Integr Comp Physiol. 2008 Feb; 294(2):R384-92. View in: PubMed

  54. Prendergast BJ, Kampf-Lassin A, Yee JR, Galang J, McMaster N, Kay LM. Winter day lengths enhance T lymphocyte phenotypes, inhibit cytokine responses, and attenuate behavioral symptoms of infection in laboratory rats. Brain Behav Immun. 2007 Nov; 21(8):1096-108. View in: PubMed

  55. Freeman DA, Kampf-Lassin A, Galang J, Wen JC, Prendergast BJ. Melatonin acts at the suprachiasmatic nucleus to attenuate behavioral symptoms of infection. Behav Neurosci. 2007 Aug; 121(4):689-97. View in: PubMed

  56. Wen JC, Prendergast BJ. Photoperiodic regulation of behavioral responsiveness to proinflammatory cytokines. Physiol Behav. 2007 Apr 23; 90(5):717-25. View in: PubMed

  57. Freeman DA, Teubner BJ, Smith CD, Prendergast BJ. Exogenous T3 mimics long day lengths in Siberian hamsters. Am J Physiol Regul Integr Comp Physiol. 2007 Jun; 292(6):R2368-72. View in: PubMed

  58. Wen JC, Dhabhar FS, Prendergast BJ. Pineal-dependent and -independent effects of photoperiod on immune function in Siberian hamsters (Phodopus sungorus). Horm Behav. 2007 Jan; 51(1):31-9. View in: PubMed

  59. Prendergast BJ, Hotchkiss AK, Wen J, Horton TH, Nelson RJ. Refractoriness to short day lengths augments tonic and gonadotrophin-releasing hormone-stimulated lutenising hormone secretion. J Neuroendocrinol. 2006 May; 18(5):339-48. View in: PubMed

  60. Beeler JA, Prendergast B, Zhuang X. Low amplitude entrainment of mice and the impact of circadian phase on behavior tests. Physiol Behav. 2006 May 30; 87(5):870-80. View in: PubMed

  61. Prendergast BJ. Internalization of seasonal time. Horm Behav. 2005 Dec; 48(5):503-11. View in: PubMed

  62. Prendergast BJ, Nelson RJ. Affective responses to changes in day length in Siberian hamsters (Phodopus sungorus). Psychoneuroendocrinology. 2005 Jun; 30(5):438-52. View in: PubMed

  63. Prendergast BJ, Bilbo SD, Nelson RJ. Short day lengths enhance skin immune responses in gonadectomised Siberian hamsters. J Neuroendocrinol. 2005 Jan; 17(1):18-21. View in: PubMed

  64. Prendergast BJ, Renstrom RA, Nelson RJ. Genetic analyses of a seasonal interval timer. J Biol Rhythms. 2004 Aug; 19(4):298-311. View in: PubMed

  65. Detillion CE, Craft TK, Glasper ER, Prendergast BJ, DeVries AC. Social facilitation of wound healing. Psychoneuroendocrinology. 2004 Sep; 29(8):1004-11. View in: PubMed

  66. Prendergast BJ, Bilbo SD, Dhabhar FS, Nelson RJ. Effects of photoperiod history on immune responses to intermediate day lengths in Siberian hamsters (Phodopus sungorus). J Neuroimmunol. 2004 Apr; 149(1-2):31-9. View in: PubMed

  67. Prendergast BJ, Hotchkiss AK, Nelson RJ. Photoperiodic regulation of circulating leukocytes in juvenile Siberian hamsters: mediation by melatonin and testosterone. J Biol Rhythms. 2003 Dec; 18(6):473-80. View in: PubMed

  68. Prendergast BJ, Hotchkiss AK, Bilbo SD, Nelson RJ. Peripubertal immune challenges attenuate reproductive development in male Siberian hamsters (Phodopus sungorus). Biol Reprod. 2004 Mar; 70(3):813-20. View in: PubMed

  69. Bilbo SD, Quan N, Prendergast BJ, Bowers SL, Nelson RJ. Photoperiod alters the time course of brain cyclooxygenase-2 expression in Siberian hamsters. J Neuroendocrinol. 2003 Oct; 15(10):958-64. View in: PubMed

  70. Prendergast BJ, Bilbo SD, Nelson RJ. Photoperiod controls the induction, retention, and retrieval of antigen-specific immunological memory. Am J Physiol Regul Integr Comp Physiol. 2004 Jan; 286(1):R54-60. View in: PubMed

  71. Piatkowska JM, Prendergast BJ, Gorman MR. Temporal integration of melatonin infusion duration: signal averaging versus frequency dependence. J Pineal Res. 2003 Sep; 35(2):91-7. View in: PubMed

  72. Kinsey SG, Prendergast BJ, Nelson RJ. Photoperiod and stress affect wound healing in Siberian hamsters. Physiol Behav. 2003 Feb; 78(2):205-11. View in: PubMed

  73. Prendergast BJ, Hotchkiss AK, Bilbo SD, Kinsey SG, Nelson RJ. Photoperiodic adjustments in immune function protect Siberian hamsters from lethal endotoxemia. J Biol Rhythms. 2003 Feb; 18(1):51-62. View in: PubMed

  74. Prendergast BJ, Mosinger B, Kolattukudy PE, Nelson RJ. Hypothalamic gene expression in reproductively photoresponsive and photorefractory Siberian hamsters. Proc Natl Acad Sci U S A. 2002 Dec 10; 99(25):16291-6. View in: PubMed

  75. Nelson RJ, Prendergast BJ. Form over function? J Biol Rhythms. 2002 Oct; 17(5):406-9; discussion 410-2. View in: PubMed

  76. Prendergast BJ, Wynne-Edwards KE, Yellon SM, Nelson RJ. Photorefractoriness of immune function in male Siberian hamsters (Phodopus sungorus). J Neuroendocrinol. 2002 Apr; 14(4):318-29. View in: PubMed

  77. Prendergast BJ, Freeman DA, Zucker I, Nelson RJ. Periodic arousal from hibernation is necessary for initiation of immune responses in ground squirrels. Am J Physiol Regul Integr Comp Physiol. 2002 Apr; 282(4):R1054-62. View in: PubMed

  78. Prendergast BJ, Nelson RJ. Spontaneous "regression" of enhanced immune function in a photoperiodic rodent Peromyscus maniculatus. Proc Biol Sci. 2001 Nov 07; 268(1482):2221-8. View in: PubMed

  79. Prendergast BJ, Kriegsfeld LJ, Nelson RJ. Photoperiodic polyphenisms in rodents: neuroendocrine mechanisms, costs, and functions. Q Rev Biol. 2001 Sep; 76(3):293-325. View in: PubMed

  80. Prendergast BJ, Yellon SM, Tran LT, Nelson RJ. Photoperiod modulates the inhibitory effect of in vitro melatonin on lymphocyte proliferation in female Siberian hamsters. J Biol Rhythms. 2001 Jun; 16(3):224-33. View in: PubMed

  81. Flynn AK, Freeman DA, Zucker I, Prendergast BJ. Testicular development in Siberian hamsters depends on frequency and pattern of melatonin signals. Am J Physiol Regul Integr Comp Physiol. 2000 Oct; 279(4):R1182-9. View in: PubMed

  82. Prendergast BJ, Gorman MR, Zucker I. Establishment and persistence of photoperiodic memory in hamsters. Proc Natl Acad Sci U S A. 2000 May 09; 97(10):5586-91. View in: PubMed

  83. Prendergast BJ, Flynn AK, Zucker I. Triggering of neuroendocrine refractoriness to short-day patterns of melatonin in Siberian hamsters. J Neuroendocrinol. 2000 Apr; 12(4):303-10. View in: PubMed

  84. Prendergast BJ, Hugenberger JL. Frequency coding of melatonin signals sufficient to induce testicular growth in photoregressed Siberian hamsters. J Neuroendocrinol. 1999 Apr; 11(4):237-41. View in: PubMed

  85. Prendergast BJ, Freeman DA. Pineal-independent regulation of photo-nonresponsiveness in the Siberian hamster (Phodopus sungorus). J Biol Rhythms. 1999 Feb; 14(1):62-71. View in: PubMed

  86. Prendergast BJ, Zucker I, Yellon SM, Ringold DA, Gorman MR. Melatonin chimeras alter reproductive development and photorefractoriness in Siberian hamsters. J Biol Rhythms. 1998 Dec; 13(6):518-31. View in: PubMed

  87. Prendergast BJ, Kelly KK, Zucker I, Gorman MR. Enhanced reproductive responses to melatonin in juvenile Siberian hamsters. Am J Physiol. 1996 Oct; 271(4 Pt 2):R1041-6. View in: PubMed