Jason Maclean, PhD

The primary focus of our group is to apply a diversity of analytical tools, including network science approaches to corticalcircuit dynamics in order to: 1) establish the higher-order cellular and synaptic mechanisms that propagate spikes, 2) to build improved encoding and decoding models of single-trial circuit activity in behaving mammals, and 3) to compare and contrast sensory and motor areas of neocortex.

University of Manitoba
Winnipeg CANADA
PhD - Neurophysiology

A dynamic subset of network interactions underlies tuning to natural movements in marmoset sensorimotor cortex.
A dynamic subset of network interactions underlies tuning to natural movements in marmoset sensorimotor cortex. Res Sq. 2023 Dec 27.
PMID: 38234779

Normalization in mouse primary visual cortex.
Normalization in mouse primary visual cortex. PLoS One. 2023; 18(12):e0295140.
PMID: 38109430

Dynamic structure of motor cortical neuron coactivity carries behaviorally relevant information.
Dynamic structure of motor cortical neuron coactivity carries behaviorally relevant information. Netw Neurosci. 2023; 7(2):661-678.
PMID: 37397877

Normalization in mouse primary visual cortex.
Normalization in mouse primary visual cortex. bioRxiv. 2023 Apr 18.
PMID: 37131716

Large-Scale Algorithmic Search Identifies Stiff and Sloppy Dimensions in Synaptic Architectures Consistent With Murine Neocortical Wiring.
Large-Scale Algorithmic Search Identifies Stiff and Sloppy Dimensions in Synaptic Architectures Consistent With Murine Neocortical Wiring. Neural Comput. 2022 11 08; 34(12):2347-2373.
PMID: 36283042

Sequential addition of neuronal stem cell temporal cohorts generates a feed-forward circuit in the Drosophila larval nerve cord.
Sequential addition of neuronal stem cell temporal cohorts generates a feed-forward circuit in the Drosophila larval nerve cord. Elife. 2022 06 20; 11.
PMID: 35723253

Validating markerless pose estimation with 3D X-ray radiography.
Validating markerless pose estimation with 3D X-ray radiography. J Exp Biol. 2022 05 01; 225(9).
PMID: 35466360

Chronic wireless neural population recordings with common marmosets.
Chronic wireless neural population recordings with common marmosets. Cell Rep. 2021 07 13; 36(2):109379.
PMID: 34260919

Cyclic transitions between higher order motifs underlie sustained asynchronous spiking in sparse recurrent networks.
Cyclic transitions between higher order motifs underlie sustained asynchronous spiking in sparse recurrent networks. PLoS Comput Biol. 2020 09; 16(9):e1007409.
PMID: 32997658

Network Analysis of Murine Cortical Dynamics Implicates Untuned Neurons in Visual Stimulus Coding.
Network Analysis of Murine Cortical Dynamics Implicates Untuned Neurons in Visual Stimulus Coding. Cell Rep. 2020 04 14; 31(2):107483.
PMID: 32294431

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